'The first presentation was about the many achievements the decoding of the genome has brought. Then I spoke and said that this century will be remembered for how little, and not how much, happened in this field.'<blockquote>
SPIEGEL: So the Human Genome Project has had very little medical benefits so far?
Venter: Close to zero to put it precisely.
SPIEGEL: Did it at least provide us with some new knowledge?
Venter: It certainly has. Eleven years ago, we didn't even know how many genes humans have. Many estimated that number at 100,000, and some went as high as 300,000. We made a lot of enemies when we claimed that there appeared to be considerably fewer -- probably closer to the neighborhood of 40,000! And then we found out that there are only half as many. I was just in Stockholm for the 200th anniversary of the Karolinska Institute. The first presentation was about the many achievements the decoding of the genome has brought. Then I spoke and said that this century will be remembered for how little, and not how much, happened in this field.
SPIEGEL: Why is it taking so long for the results of genome research to be applied in medicine?
Venter: Because we have, in truth, learned nothing from the genome other than probabilities. How does a 1 or 3 percent increased risk for something translate into the clinic? It is useless information.
...
...the genome. We know nothing.
...
Venter: Well, the goal is multifold. We have to start by creating minimal cells. A human cell is too complex -- we have no idea how any human cell works. We don't even know how the simplest bacterial cell works.
...
Venter: … yes, they are investing $600 million in the project, with half going to our partnership. It's a good round number. It's the same money that PerkinElmer gave me to decode the human genome. With it, we sequenced the human genome in nine months instead of many, many years. The public money that flowed into the Human Genome Project, above all, created an enormous, inflexible bureaucracy. And it is only because of private money that we can now sail across the ocean with this sailboat and discover 40 million genes -- there are only 41 million genes known to all of science. All you need are a few innovative ideas and independent funding to allow you to do things that other people can only dream about.
- 'We Have Learned Nothing from the Genome',
page 2,
page 3, 07/29/2010</blockquote>